How do intestinal microbiota interact with host genome-encoded
processes to impact vertebrate health and disease
?

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2017 May 22 - The Rawls lab is happy to announce that Cece Kelly, a graduate student in the Cell and Molecular Biology Program, has joined the lab to conduct her thesis research.  She received her B.S. in Biochemistry from the University of New Mexico in 2016, where she trained with Dr. Irene Salinas.

2017 April 5
- Congratulations to Jim Davison on his successful defense of his Ph.D. dissertation entitled “Identification of transcription regulatory mechanisms mediating host responses to the microbiota in the intestinal epithelium”!

2017 April 1
- Jim Davison, Colin Lickwar, John Rawls, and colleagues publish an article entitled "Microbiota regulate intestinal epithelial gene expression by suppressing an ancient transcription factor’ in Genome Research (PMID: 28385711). This article was also highlighted in DukeToday.                                                                                        

2017 March 27
- James Minchin and John Rawls publish an article entitled "A classification system for zebrafish adipose tissues” in Disease Models & Mechanisms (PMID: 28348140).

2017 March 7
- John Rawls and colleagues publish a review article entitled "Integrative physiology: at the crossroads of nutrition, microbiota and animal physiology” in Cell Metabolism (PMID: 28273475).

2017 February 2
- Rawls lab members contribute to two chapters in new issue of Methods in Cell Biology including methods for analysis of adipose tissues and host-microbiota interactions in zebrafish (PMID: 28129849 and 28129860).

2017 January 9
- The Rawls lab is happy to welcome Dr. Jessica McCann who joins us as a research associate senior after completing her postdoctoral training with Dr. Patrick Seed.

2016 December 1
- The Rawls lab is happy to welcome three new lab members!  Michael Hoy is joining us as a rotating graduate student in Duke’s Cell and Molecular Biology Program. Lysk Wyckoff and Alvin Han joined the lab as undergraduate research assistants.

2016 November 28
- Dr. Rawls is named as a Fellow of the American Association for the Advancement of Science (read more).

2016 November 23 - The Rawls and Valdivia labs publish "Genomic sequencing-based mutational enrichment analysis identifies motility genes in a genetically intractable gut microbe" in PNAS (PMID: 27911803). This paper was also highlighted in the Duke Med School Blog "Unlocking the Secrets of the Gut Microbiome".

2016 August 22
- The Rawls lab is happy to welcome two new lab members!  Dr. Jia Wen is joining us as a postdoctoral fellow after completing her Ph.D. With Dr. Elizabeth Fozo at the University of Tennessee.  Cecelia Kelly is joining us as a rotating graduate student in Duke’s Cell and Molecular Biology Program.

2016 July 15
- The Rawls lab bids farewell to James Minchin as he leaves to become a principal investigator at the BHF Centre for Cardiovascular Science at the University of Edinburgh.

2016 July 1
- The Rawls lab bids farewell to Jordan Cocchiaro who is starting a new position as a Program Manager for the Duke Human Vaccine Institute.

2016 May 20
- The Rawls lab bids farewell to Sheila Janardhan as she leaves to begin medical school at the University of Missouri at Kansas City.  We are also happy to welcomes Rebecca Graham who joins us as a research technician after completing her BS at the University of Arkansas at Pine Bluff.

2016 April 1
- The Rawls lab celebrates its 10th anniversary!

2016 March 15
- The Rawls lab is happy to welcome Ben Arnson, a rotating graduate student in the Cell and Molecular Biology Program, and Shelby Priest, a rotating graduate student in the Molecular Genetics and Microbiology Program.

2016 January 13
- John Rawls and other colleagues at Duke publish "The severity of NAFLD is associated with gut dysbiosis and shift in the metabolic function of the gut microbiota” in Hepatology (PMID:26600078). This paper was also highlighted in: Nature Reviews Gastroenterology and Hepatology (“NAFLD severity associated with gut dysbiosis” by Hugh Thomas, 09/12/15).

2015 December 9
- Sol Gomez de la Torre Canny and John Rawls publish a Preview in Cell Host & Microbe entitled "Baby it’s cold outside:  Host-microbiota relationships drive temperature adaptations" (PMID: 26651935) reviewing recent work from the lab of Mirko Trajkovski (PMID: 26638070).

2015 November 30
- The Rawls lab is happy to welcome Daniel Grigsby, a rotating graduate student in the University Program in Genetics and Genomics.

2015 November 9
- The Rawls lab is happy to welcome Karolina Woroniecka, a rotating graduate student in the Medical Scientist Training Program.

2015 October 5
- The Rawls lab is happy to welcome Rui Dai, a rotating graduate student in the Medical Scientist Training Program.

2015 September 29
– Sandi Wong, John Rawls and colleagues in Brendan Bohannan and Karen Guillemin’s labs publish "Ontogenetic differences in dietary fat influence microbiota assembly in the zebrafish gut" in MBio (PMID: 26419876).

2015 September 15
– Ted Espenschied, John Rawls and colleagues in Dennis Ko and David Tobin’s labs publish "CPAG: software for leveraging pleiotropy in GWAS to reveal similarity between human traits links plasma fatty acids and intestinal inflammation” in Genome Biology (PMID: 26374098).
This paper was also highlighted in:
Duke TODAY (“Specific Fatty Acids May Worsen Crohn’s Disease” by Karl Bates, 15/09/15)
IBD News Today (“Certain Fatty Acids May Worsen Inflammation in Crohn’s Disease” by Anna Tan, 16/09/15)
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2015 September 4
Sandi Wong, John Rawls and colleagues in Brendan Bohannan and Karen Guillemin’s labs publish "The composition of the zebrafish intestinal microbial community varies across development" in ISME Journal (PMID: 26339860).

2015 September 3
Duke University and NC A&T have been awarded a National Science Foundation Research Traineeship grant to establish a training program for graduate students who are interested in microbiome research.  This program, entitled “Integrative Bioinformatics for Investigating and Engineering Microbiomes” (IBIEM), is designed to transcend communication barriers between disciplines and promote team science. Press release.

2015 August 21
– Sandi Wong, John Rawls and colleagues in Brendan Bohannan and Karen Guillemin’s labs publish "Contribution of neutral processes to the assembly of gut microbial communities in the zebrafish over host development" in ISME Journal (PMID: 26296066).

2015 August 17
- The Rawls lab is happy to welcome two new lab members!  Dr. Lihua Ye is joining us as a Postdoctoral Fellow after completing her Ph.D. in the lab of Dr. Ryan Anderson at the University of Indiana School of Medicine. Sheila Janardhan is joining us as a Research Technician after recently receiving her B.A. from Duke University.

2015 August 3 - Jordan Cocchiaro, Jim Davison, and John Rawls participated in the inaugural “Frontiers in Host-Microbe Interactions” course at the Marine Biological Laboratory at Woods Hole MA.

2015 April 10 - Congratulations to Sandi Wong on her successful defense of her Ph.D. dissertation entitled “Assembly of intestinal microbiota is determined by host development, diet, and environment”!

2015 March 31 - Congratulations to Caitlin Murdoch on her receipt of a 2015 National Science Foundation Graduate Research Fellowship!

2015 March 30 - An article features a collaboration between the Rawls and Magness labs supported by the Clinical and Translational Science Awards (CTSAs) at Duke and UNC.

2015 March 23 – James Minchin, Chris Harvey, John Rawls and colleagues publish “Plexin D1 determines body fat distribution by regulating the type V collagen microenvironment in visceral adipose tissue." in PNAS (PMID: 25831505Cover).
This paper was also highlighted in:
Financial TImes 
Yahoo! Health 
Daily Mail

2015 February 17 - Jordan Cocchiaro, John Rawls and colleagues publish "Epigenetic control of intestinal barrier function and inflammation in zebrafish." in PNAS (PMID: 25730872; Cover)

2014 December 1 - The Rawls lab is happy to welcome Jamie Garcia, a rotating graduate student in the Cell & Molecular Biology Graduate Program.

2014 October 15 - The Rawls lab is happy to welcome a new undergraduate work-study student, Conor Guest.

2014 June 24 - Gray Camp, Colin Lickwar, John Rawls and colleagues publish "Microbiota modulate transcription in the intestinal epithelium without remodeling the accessible chromatin landscape." in Genome Research(PMID: 24963153; Data; Cover)

2014 May 19 - The Rawls lab is happy to announce that Caitlin Murdoch and Ted Espenschied, both graduate students in the Molecular Genetics & Microbiology Program, have joined the lab to conduct their thesis research.

2014 April 21 - The Rawls lab is happy to welcome a new Postdoc to the lab.  Dr. Sol  Gomez de la Torre Canny is joining us after completing  her  PhD  in the lab of Dr. Daniel Wagner of Rice University.

2014 January 8th - The Rawls lab is happy to welcome a new undergrad work-study student, Howard Deng. Howard studies environmental sciences.

2013 December 26 - Michelle Kanther, Ed Flynn, John Rawls and colleagues publish "Commensal microbiota stimulate systemic neutrophil migration through induction of Serum amyloid A" in Cellular Microbiology (PMID: 24373309)

2013 November 14 - The Rawls lab is happy to welcome several new members - Michael Davidson is a rotating graduate student in the Medical Scientist Training Program, Ted Espenschied is a rotating graduate student in the Molecular Genetics & Microbiology Graduate Program, and Patrick Williams is joining us as a research technician.

2013 October 15 - The Rawls lab and other Duke microbiome researchers are featured in an article in GenomeLIFE entitled "Microbe R Us".

2013 August 26 - The Rawls lab is happy to welcome several new members - Caitlin Murdoch is a rotating graduate student in the Molecular Genetics & Microbiology Graduate Program, Adriana Guzman Holst is an undergraduate student conducting independent study, and Dustin Hadfield is an undergraduate work-study student.

2013 July 01 – The Rawls Lab moves to Duke University.

2013 June 14 - Sandi Wong, John Rawls, and colleagues publish “Aquacultured rainbow trout (Oncorhynchus mykiss) possess a large core intestinal microbiota that is resistant to variation in diet and rearing density” in Applied & Environmental Microbiology (PMID: 23770898).

2013 June 12 - James Minchin, John Rawls and colleagues publish “In vivo lineage tracing identifies oesophageal and sternohyal muscles as novel Pax3-dependent migratory somite derivatives essential for ingestion” in Development (PMID: 23760954).

2013 June 7 – John Rawls and colleagues publish “Getting the inside tract: New frontiers in zebrafish digestive system biology” to introduce a special issue of Zebrafish entitled “The Zebrafish Digestive System: Biology to Disease” (PMID: 23738756).

2013 May 31 – Postdoctoral fellow Dr. James Minchin is awarded a 1-year postdoctoral fellowship from the American Heart Association entitled “Plexin D1 regulates visceral adipose tissue growth in zebrafish”.

2013 May 29 - John Rawls and colleagues publish “Mucosal candidiasis elicits activation of NF-κB, proinflammatory gene expression and localized neutrophilia in a transparent vertebrate host” in Disease Models & Mechanisms (PMID: 23720235).

2013 March 1 – James Minchin, John Rawls and colleagues publish “Dwarfism and increased adiposity in the growth hormone 1 mutant zebrafish vizzini” in Endocrinology (PMID: 23456361).

2013 Feb 20 – Jordan Cocchiaro and John Rawls publish “Microgavage of the larval zebrafish intestine” in Journal of Visual Experiments (PMID: 23463135).

2013 Feb 7 - John Rawls and colleagues publish "Animals in a bacterial world, a new imperative for the life sciences" in PNAS (PMID: 23391737)
This paper was also highlighted in:
     -ASM’s “Small Things Considered” “
Whose planet is it anyway?” 
     -PhysOrg “
We are living in a bacterial world, and it's impacting us more than previously          thought

2012 Dec 22 – Lantz Mackey, John Rawls and colleagues publish “Carbon monoxide and heme oxygenase-1 maintain intestinal homeostasis in mice through augmented bacterial clearance” in Gastroenterology (PMID: 23266559).

2012 Sep 13 - Ivana Semova, Lantz Mackey, John Rawls and colleagues publish "Microbiota regulate intestinal absorption and metabolism of fatty acids in the zebrafish" in Cell Host & Microbe (PMID: 22980325).  
This paper was also highlighted in:
     - Cell Host & Microbe
Gut Microbes Make for Fattier Fish”.
     - Faculty of 1000
     - Scientific American
The Food Fight in Your Gut: Why Bacteria Will Change the Way
    You Think about Calories

     - Smithsonian
Biologists Pinpoint Bacteria That Increase Digestive Intake of Fat” 
     - AAAS’s “EurekAlert” “
Gut Microbes Help the Body Extract More Calories from Food